Establishment and characteristics of a cisplatin-resistant KB cell line.
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چکیده
منابع مشابه
Establishment and characterization of a cisplatin-resistant cell line, KB-R, derived from oral carcinoma cell line, KB.
To investigate the mechanism of the resistance to cisplatin (CDDP), we established the CDDP-resistant cell line, KB-R, from CDDP-sensitive oral carcinoma cell line, KB. The 3-(3, 4-dimethyl-thiazol-2-yl) 2, 5-diphenyltetrazolium bromide (MTT) assay indicated that KB-R is 5.5-fold more resistant to CDDP than KB. Microarray analysis indicated that the expression levels of 1,718 genes were elevate...
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ژورنال
عنوان ژورنال: Practica Oto-Rhino-Laryngologica
سال: 1990
ISSN: 1884-4545,0032-6313
DOI: 10.5631/jibirin.83.1591